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Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka

BACKGROUND: Diabetes is one of the world's biggest health problems and the disease affects almost all organ systems. The relationship between type 2 diabetes mellitus (T2DM) and bone mineral density (BMD) has been controversial. Early identification of reduction in bone mass in a diabetic patie...

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Autores principales: Asokan, Athulya G., Jaganathan, Jayakumar, Philip, Rajeev, Soman, Rino Roopak, Sebastian, Shibu Thomas, Pullishery, Fawaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320831/
https://www.ncbi.nlm.nih.gov/pubmed/28250682
http://dx.doi.org/10.4103/0976-9668.198363
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author Asokan, Athulya G.
Jaganathan, Jayakumar
Philip, Rajeev
Soman, Rino Roopak
Sebastian, Shibu Thomas
Pullishery, Fawaz
author_facet Asokan, Athulya G.
Jaganathan, Jayakumar
Philip, Rajeev
Soman, Rino Roopak
Sebastian, Shibu Thomas
Pullishery, Fawaz
author_sort Asokan, Athulya G.
collection PubMed
description BACKGROUND: Diabetes is one of the world's biggest health problems and the disease affects almost all organ systems. The relationship between type 2 diabetes mellitus (T2DM) and bone mineral density (BMD) has been controversial. Early identification of reduction in bone mass in a diabetic patient may be helpful in preventing the bone loss and future fracture risks. OBJECTIVE: The aim is to study the effect of T2DM on BMD among patients in South Karnataka. MATERIALS AND METHODS: A cross-sectional study was conducted on 150 patients between 40 and 70 years of age which included 75 diabetic and 75 nondiabetic subjects. BMD was measured using qualitative ultrasound and the data were compared among age-matched subjects of both the groups. Statistical analysis was performed using unpaired Student's t-test and test of equality of proportions. RESULTS: No significant difference was observed in bone density of both the groups. On further analyzing the data, incidence of osteoporosis was higher among diabetic subjects, whereas incidence of osteopenia was higher among nondiabetic subjects. CONCLUSION: Although significant difference in bone mineral density was not observed in both the groups, the incidence of osteoporosis was higher among type 2 diabetics. Hence, all type 2 diabetics should be evaluated for the risk of osteoporosis and should be offered appropriate preventive measures.
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spelling pubmed-53208312017-03-01 Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka Asokan, Athulya G. Jaganathan, Jayakumar Philip, Rajeev Soman, Rino Roopak Sebastian, Shibu Thomas Pullishery, Fawaz J Nat Sci Biol Med Original Article BACKGROUND: Diabetes is one of the world's biggest health problems and the disease affects almost all organ systems. The relationship between type 2 diabetes mellitus (T2DM) and bone mineral density (BMD) has been controversial. Early identification of reduction in bone mass in a diabetic patient may be helpful in preventing the bone loss and future fracture risks. OBJECTIVE: The aim is to study the effect of T2DM on BMD among patients in South Karnataka. MATERIALS AND METHODS: A cross-sectional study was conducted on 150 patients between 40 and 70 years of age which included 75 diabetic and 75 nondiabetic subjects. BMD was measured using qualitative ultrasound and the data were compared among age-matched subjects of both the groups. Statistical analysis was performed using unpaired Student's t-test and test of equality of proportions. RESULTS: No significant difference was observed in bone density of both the groups. On further analyzing the data, incidence of osteoporosis was higher among diabetic subjects, whereas incidence of osteopenia was higher among nondiabetic subjects. CONCLUSION: Although significant difference in bone mineral density was not observed in both the groups, the incidence of osteoporosis was higher among type 2 diabetics. Hence, all type 2 diabetics should be evaluated for the risk of osteoporosis and should be offered appropriate preventive measures. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5320831/ /pubmed/28250682 http://dx.doi.org/10.4103/0976-9668.198363 Text en Copyright: © 2017 Journal of Natural Science, Biology and Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Asokan, Athulya G.
Jaganathan, Jayakumar
Philip, Rajeev
Soman, Rino Roopak
Sebastian, Shibu Thomas
Pullishery, Fawaz
Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka
title Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka
title_full Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka
title_fullStr Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka
title_full_unstemmed Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka
title_short Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka
title_sort evaluation of bone mineral density among type 2 diabetes mellitus patients in south karnataka
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320831/
https://www.ncbi.nlm.nih.gov/pubmed/28250682
http://dx.doi.org/10.4103/0976-9668.198363
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