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Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer’s disease

Increasing research suggests that mitochondrial defects play a major role in Alzheimer’s disease (AD) pathogenesis. We aimed to better understand changes in mitochondria with the development and progression of AD. We compared APPsw/PS1dE9 transgenic mice at 3, 6, 9, and 12 months old as an animal mo...

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Detalles Bibliográficos
Autores principales:	Xu, Lin-Lin, Shen, Yang, Wang, Xiao, Wei, Li-Fei, Wang, Ping, Yang, Hui, Wang, Cun-Fu, Xie, Zhao-Hong, Bi, Jian-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Cellular, Molecular and Developmental Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321113/ https://www.ncbi.nlm.nih.gov/pubmed/28118288 http://dx.doi.org/10.1097/WNR.0000000000000739

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