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Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases

Mitochondrial DNA (mtDNA) has many similarities with bacterial DNA because of their shared common ancestry. Increasing evidence demonstrates mtDNA to be a potent danger signal that is recognised by the innate immune system and can directly modulate the inflammatory response. In humans, elevated circ...

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Detalles Bibliográficos
Autores principales: Boyapati, Ray K., Tamborska, Arina, Dorward, David A., Ho, Gwo-Tzer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321122/
https://www.ncbi.nlm.nih.gov/pubmed/28299196
http://dx.doi.org/10.12688/f1000research.10397.1