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Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases
Mitochondrial DNA (mtDNA) has many similarities with bacterial DNA because of their shared common ancestry. Increasing evidence demonstrates mtDNA to be a potent danger signal that is recognised by the innate immune system and can directly modulate the inflammatory response. In humans, elevated circ...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321122/ https://www.ncbi.nlm.nih.gov/pubmed/28299196 http://dx.doi.org/10.12688/f1000research.10397.1 |