Cargando…
Recent advances in Major Histocompatibility Complex (MHC) class I antigen presentation: Plastic MHC molecules and TAPBPR-mediated quality control
We have known since the late 1980s that the function of classical major histocompatibility complex (MHC) class I molecules is to bind peptides and display them at the cell surface to cytotoxic T cells. Recognition by these sentinels of the immune system can lead to the destruction of the presenting...
Autores principales: | van Hateren, Andy, Bailey, Alistair, Elliott, Tim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321123/ https://www.ncbi.nlm.nih.gov/pubmed/28299193 http://dx.doi.org/10.12688/f1000research.10474.1 |
Ejemplares similares
-
TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst
por: Hermann, Clemens, et al.
Publicado: (2015) -
TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway
por: Neerincx, Andreas, et al.
Publicado: (2017) -
Chaperone function in antigen presentation by MHC class I molecules—tapasin in the PLC and TAPBPR beyond
por: Margulies, David H., et al.
Publicado: (2023) -
Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function
por: van Hateren, Andy, et al.
Publicado: (2015) -
The glycosylation status of MHC class I molecules impacts their interactions with TAPBPR
por: Ilca, F. Tudor, et al.
Publicado: (2021)