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Recent advances in Major Histocompatibility Complex (MHC) class I antigen presentation: Plastic MHC molecules and TAPBPR-mediated quality control

We have known since the late 1980s that the function of classical major histocompatibility complex (MHC) class I molecules is to bind peptides and display them at the cell surface to cytotoxic T cells. Recognition by these sentinels of the immune system can lead to the destruction of the presenting...

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Detalles Bibliográficos
Autores principales: van Hateren, Andy, Bailey, Alistair, Elliott, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321123/
https://www.ncbi.nlm.nih.gov/pubmed/28299193
http://dx.doi.org/10.12688/f1000research.10474.1

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