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Evaluating the Effectiveness of GTM-1, Rapamycin, and Carbamazepine on Autophagy and Alzheimer Disease

BACKGROUND: This study was proposed to compare the efficacy and safety of GTM-1, Rapamycin (Rap), and Carbamazepine (CBZ) in managing Alzheimer disease (AD). The impact of the above mentioned therapeutic drugs on autophagy was also investigated in our study. MATERIAL/METHODS: Firstly, 3×Tg AD mice w...

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Detalles Bibliográficos
Autores principales: Zhang, Lijuan, Wang, Lina, Wang, Run, Gao, Yuan, Che, Haoyue, Pan, Yonghua, Fu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321171/
https://www.ncbi.nlm.nih.gov/pubmed/28193995
http://dx.doi.org/10.12659/MSM.898679