Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model

Neuropathic pain is still an extremely important problem in today’s medicine because opioids, which are commonly used to reduce pain, have limited efficacy in this type of pathology. Therefore, complementary therapy is needed. Our experiments were performed in rats to evaluate the contribution of th...

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Detalles Bibliográficos
Autores principales: Jurga, Agnieszka M., Piotrowska, Anna, Makuch, Wioletta, Przewlocka, Barbara, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321202/
https://www.ncbi.nlm.nih.gov/pubmed/28275350
http://dx.doi.org/10.3389/fphar.2017.00048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321202/
https://www.ncbi.nlm.nih.gov/pubmed/28275350
http://dx.doi.org/10.3389/fphar.2017.00048

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