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Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model
Neuropathic pain is still an extremely important problem in today’s medicine because opioids, which are commonly used to reduce pain, have limited efficacy in this type of pathology. Therefore, complementary therapy is needed. Our experiments were performed in rats to evaluate the contribution of th...
Autores principales: | Jurga, Agnieszka M., Piotrowska, Anna, Makuch, Wioletta, Przewlocka, Barbara, Mika, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321202/ https://www.ncbi.nlm.nih.gov/pubmed/28275350 http://dx.doi.org/10.3389/fphar.2017.00048 |
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