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Cost-effectiveness of club-foot treatment in low-income and middle-income countries by the Ponseti method

BACKGROUND: Club foot is a common congenital deformity affecting 150 000–200 000 children every year. Untreated patients end up walking on the side or back of the affected foot, with severe social and economic consequences. Club foot is highly treatable by the Ponseti method, a non-invasive techniqu...

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Autores principales: Grimes, Caris E, Holmer, Hampus, Maraka, Jane, Ayana, Birhanu, Hansen, Linda, Lavy, Christopher B D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321308/
https://www.ncbi.nlm.nih.gov/pubmed/28588918
http://dx.doi.org/10.1136/bmjgh-2015-000023
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author Grimes, Caris E
Holmer, Hampus
Maraka, Jane
Ayana, Birhanu
Hansen, Linda
Lavy, Christopher B D
author_facet Grimes, Caris E
Holmer, Hampus
Maraka, Jane
Ayana, Birhanu
Hansen, Linda
Lavy, Christopher B D
author_sort Grimes, Caris E
collection PubMed
description BACKGROUND: Club foot is a common congenital deformity affecting 150 000–200 000 children every year. Untreated patients end up walking on the side or back of the affected foot, with severe social and economic consequences. Club foot is highly treatable by the Ponseti method, a non-invasive technique that has been described as highly suitable for use in resource-limited settings. To date, there has been no evaluation of its cost-effectiveness ratio, defined as the cost of averting one disability-adjusted life year (DALY), a composite measure of the impact of premature death and disability. In this study, we aimed to calculate the average cost-effectiveness ratio of the Ponseti method for correcting club foot in sub-Saharan Africa. METHODS: Using data from 12 sub-Saharan African countries provided by the international non-profit organisation CURE Clubfoot, which implements several Ponseti treatment programmes around the world, we estimated the average cost of the point-of-care treatment for club foot in these countries. We divided the cost of treatment with the average number of DALYs that can be averted by the Ponseti treatment, assuming treatment is successful in 90% of patients. RESULTS: We found the average cost of the Ponseti treatment to be US$167 per patient. The average number of DALYs averted was 7.42, yielding a cost-effectiveness ratio of US$22.46 per DALY averted. To test the robustness of our calculation different variables were used and these yielded a cost range of US$5.28–29.75. This is less than a tenth of the cost of many other treatment modalities used in resource-poor settings today. CONCLUSIONS: The Ponseti method for the treatment of club foot is cost-effective and practical in a low-income country setting. These findings could be used to raise the priority for implementing Ponseti treatment in areas where patients are still lacking access to the life-changing intervention.
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spelling pubmed-53213082017-06-06 Cost-effectiveness of club-foot treatment in low-income and middle-income countries by the Ponseti method Grimes, Caris E Holmer, Hampus Maraka, Jane Ayana, Birhanu Hansen, Linda Lavy, Christopher B D BMJ Glob Health Research BACKGROUND: Club foot is a common congenital deformity affecting 150 000–200 000 children every year. Untreated patients end up walking on the side or back of the affected foot, with severe social and economic consequences. Club foot is highly treatable by the Ponseti method, a non-invasive technique that has been described as highly suitable for use in resource-limited settings. To date, there has been no evaluation of its cost-effectiveness ratio, defined as the cost of averting one disability-adjusted life year (DALY), a composite measure of the impact of premature death and disability. In this study, we aimed to calculate the average cost-effectiveness ratio of the Ponseti method for correcting club foot in sub-Saharan Africa. METHODS: Using data from 12 sub-Saharan African countries provided by the international non-profit organisation CURE Clubfoot, which implements several Ponseti treatment programmes around the world, we estimated the average cost of the point-of-care treatment for club foot in these countries. We divided the cost of treatment with the average number of DALYs that can be averted by the Ponseti treatment, assuming treatment is successful in 90% of patients. RESULTS: We found the average cost of the Ponseti treatment to be US$167 per patient. The average number of DALYs averted was 7.42, yielding a cost-effectiveness ratio of US$22.46 per DALY averted. To test the robustness of our calculation different variables were used and these yielded a cost range of US$5.28–29.75. This is less than a tenth of the cost of many other treatment modalities used in resource-poor settings today. CONCLUSIONS: The Ponseti method for the treatment of club foot is cost-effective and practical in a low-income country setting. These findings could be used to raise the priority for implementing Ponseti treatment in areas where patients are still lacking access to the life-changing intervention. BMJ Publishing Group 2016-05-26 /pmc/articles/PMC5321308/ /pubmed/28588918 http://dx.doi.org/10.1136/bmjgh-2015-000023 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Research
Grimes, Caris E
Holmer, Hampus
Maraka, Jane
Ayana, Birhanu
Hansen, Linda
Lavy, Christopher B D
Cost-effectiveness of club-foot treatment in low-income and middle-income countries by the Ponseti method
title Cost-effectiveness of club-foot treatment in low-income and middle-income countries by the Ponseti method
title_full Cost-effectiveness of club-foot treatment in low-income and middle-income countries by the Ponseti method
title_fullStr Cost-effectiveness of club-foot treatment in low-income and middle-income countries by the Ponseti method
title_full_unstemmed Cost-effectiveness of club-foot treatment in low-income and middle-income countries by the Ponseti method
title_short Cost-effectiveness of club-foot treatment in low-income and middle-income countries by the Ponseti method
title_sort cost-effectiveness of club-foot treatment in low-income and middle-income countries by the ponseti method
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321308/
https://www.ncbi.nlm.nih.gov/pubmed/28588918
http://dx.doi.org/10.1136/bmjgh-2015-000023
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