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Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo
Trichuris trichiura is a human parasitic whipworm infecting around 500 million people globally, damaging the physical growth and educational performance of those infected. Current drug treatment options are limited and lack efficacy against the worm, preventing an eradication programme. It is theref...
Autores principales: | Partridge, Frederick A., Murphy, Emma A., Willis, Nicky J., Bataille, Carole J. R., Forman, Ruth, Heyer-Chauhan, Narinder, Marinič, Bruno, Sowood, Daniel J. C., Wynne, Graham M., Else, Kathryn J., Russell, Angela J., Sattelle, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321434/ https://www.ncbi.nlm.nih.gov/pubmed/28182663 http://dx.doi.org/10.1371/journal.pntd.0005359 |
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