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Capsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes rats

Type 2 diabetes (T2D) is a high-risk factor for Alzheimer’s disease (AD) due to impaired insulin signaling pathway in brain. Capsaicin is a specific transient receptor potential vanilloid 1 (TRPV1) agonist which was proved to ameliorate insulin resistance. In this study, we investigated whether diet...

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Detalles Bibliográficos
Autores principales: Xu, Weijie, Liu, Juanhong, Ma, Delin, Yuan, Gang, Lu, Yan, Yang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321461/
https://www.ncbi.nlm.nih.gov/pubmed/28225806
http://dx.doi.org/10.1371/journal.pone.0172477