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CD4 CTL, a Cytotoxic Subset of CD4(+) T Cells, Their Differentiation and Function
CD4(+) T cells with cytotoxic activity (CD4 CTL) have been observed in various immune responses. These cells are characterized by their ability to secrete granzyme B and perforin and to kill the target cells in an MHC class II-restricted fashion. Although CD4 CTLs were once thought to be an in vitro...
Autores principales: | Takeuchi, Arata, Saito, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321676/ https://www.ncbi.nlm.nih.gov/pubmed/28280496 http://dx.doi.org/10.3389/fimmu.2017.00194 |
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