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Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation
Previous studies have revealed that nucleosomes impede elongation of RNA polymerase II (RNAPII). Recent observations suggest a role for ATP-dependent chromatin remodellers in modulating this process, but direct in vivo evidence for this is unknown. Here using fission yeast, we identify Fun30(Fft3) a...
Autores principales: | Lee, Junwoo, Shik Choi, Eun, David Seo, Hogyu, Kang, Keunsoo, Gilmore, Joshua M., Florens, Laurence, Washburn, Michael P., Choe, Joonho, Workman, Jerry L., Lee, Daeyoup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321744/ https://www.ncbi.nlm.nih.gov/pubmed/28218250 http://dx.doi.org/10.1038/ncomms14527 |
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