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Proteolysis regulates cardiomyocyte maturation and tissue integration

Tissue integrity is critical for organ formation and function. During heart development, cardiomyocytes differentiate and integrate to form a coherent tissue that contracts synchronously. However, the molecular mechanisms regulating cardiac tissue integrity are poorly understood. Here we show that p...

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Detalles Bibliográficos
Autores principales: Fukuda, Ryuichi, Gunawan, Felix, Beisaw, Arica, Jimenez-Amilburu, Vanesa, Maischein, Hans-Martin, Kostin, Sawa, Kawakami, Koichi, Stainier, Didier Y. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321751/
https://www.ncbi.nlm.nih.gov/pubmed/28211472
http://dx.doi.org/10.1038/ncomms14495

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