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Circadian deep sequencing reveals stress-response genes that adopt robust rhythmic expression during aging
Disruption of the circadian clock, which directs rhythmic expression of numerous output genes, accelerates aging. To enquire how the circadian system protects aging organisms, here we compare circadian transcriptomes in heads of young and old Drosophila melanogaster. The core clock and most output g...
Autores principales: | Kuintzle, Rachael C., Chow, Eileen S., Westby, Tara N., Gvakharia, Barbara O., Giebultowicz, Jadwiga M., Hendrix, David A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321795/ https://www.ncbi.nlm.nih.gov/pubmed/28221375 http://dx.doi.org/10.1038/ncomms14529 |
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