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Significant contribution of TRPC6 channel-mediated Ca(2+) influx to the pathogenesis of Crohn's disease fibrotic stenosis

Intestinal fibrosis is an intractable complication of Crohn's disease (CD), and, when occurring excessively, causes severe intestinal obstruction that often necessitates surgical resection. The fibrosis is characterized by an imbalance in the turnover of extracellular matrix (ECM) components, w...

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Detalles Bibliográficos
Autores principales:	Kurahara, Lin Hai, Hiraishi, Keizo, Sumiyoshi, Miho, Doi, Mayumi, Hu, Yaopeng, Aoyagi, Kunihiko, Jian, Yuwen, Inoue, Ryuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japan Society of Smooth Muscle Research 2016
Materias:	Invited Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321852/ https://www.ncbi.nlm.nih.gov/pubmed/27818466 http://dx.doi.org/10.1540/jsmr.52.78

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