Transient Treg depletion enhances therapeutic anti‐cancer vaccination

INTRODUCTION: Regulatory T cells (Treg) play an important role in suppressing anti‐ immunity and their depletion has been linked to improved outcomes. To better understand the role of Treg in limiting the efficacy of anti‐cancer immunity, we used a Diphtheria toxin (DTX) transgenic mouse model to sp...

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Detalles Bibliográficos
Autores principales: Fisher, Scott A., Aston, Wayne J., Chee, Jonathan, Khong, Andrea, Cleaver, Amanda L., Solin, Jessica N., Ma, Shaokang, Lesterhuis, W. Joost, Dick, Ian, Holt, Robert A., Creaney, Jenette, Boon, Louis, Robinson, Bruce, Lake, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322183/
https://www.ncbi.nlm.nih.gov/pubmed/28250921
http://dx.doi.org/10.1002/iid3.136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322183/
https://www.ncbi.nlm.nih.gov/pubmed/28250921
http://dx.doi.org/10.1002/iid3.136

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