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Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins
Clostridium botulinum neurotoxins (BoNTs) are the most poisonous naturally occurring protein toxins known to mankind and are the causative agents of the severe and potentially life-threatening disease botulism. They are also known for their application as cosmetics and as unique bio-pharmaceuticals...
Autores principales: | Jenkinson, Stephen P., Grandgirard, Denis, Heidemann, Martina, Tscherter, Anne, Avondet, Marc-André, Leib, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322221/ https://www.ncbi.nlm.nih.gov/pubmed/28280466 http://dx.doi.org/10.3389/fphar.2017.00073 |
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