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T-Cells Specific for a Self-Peptide of ApoB-100 Exacerbate Aortic Atheroma in Murine Atherosclerosis
On the basis of mouse I-A(b)-binding motifs, two sequences of the murine apolipoprotein B-100 (mApoB-100), mApoB-100(3501–3515) (designated P3) and mApoB-100(978–992) (designated P6), were found to be immunogenic. In this report, we show that P6 is also atherogenic. Immunization of Apoe(−/−) mice fe...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322236/ https://www.ncbi.nlm.nih.gov/pubmed/28280493 http://dx.doi.org/10.3389/fimmu.2017.00095 |