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Ambiguous presentation of Mycobacterium avium complex‐associated Rasmussen aneurysm

A 77‐year‐old man with a progressively dry cough (two months duration) was admitted with hemoptysis. Chest computed tomography (CT) revealed left lingular lobe consolidation and one thick‐walled cavity lesion over the left lower lobe, which was accompanied by satellite micro‐nodules in a tree‐in‐bud...

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Autores principales: Chiu, Hsin‐Wei, Kuo, Shu‐Hung, Lai, Ruay‐Sheng, Wu, Ming‐Ting, Wu, Hsiu‐Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322266/
https://www.ncbi.nlm.nih.gov/pubmed/28250929
http://dx.doi.org/10.1002/rcr2.219
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author Chiu, Hsin‐Wei
Kuo, Shu‐Hung
Lai, Ruay‐Sheng
Wu, Ming‐Ting
Wu, Hsiu‐Fu
author_facet Chiu, Hsin‐Wei
Kuo, Shu‐Hung
Lai, Ruay‐Sheng
Wu, Ming‐Ting
Wu, Hsiu‐Fu
author_sort Chiu, Hsin‐Wei
collection PubMed
description A 77‐year‐old man with a progressively dry cough (two months duration) was admitted with hemoptysis. Chest computed tomography (CT) revealed left lingular lobe consolidation and one thick‐walled cavity lesion over the left lower lobe, which was accompanied by satellite micro‐nodules in a tree‐in‐bud pattern. CT‐guided biopsy confirmed mycobacterial infection, and subsequent culture yielded Mycobacterium avium complex (MAC). Unremitting hemoptysis was present despite treatment (14 days) with ethambutol, rifampin, clarithromycin, and streptomycin. Initial CT angiography (CTA) to determine the source of the hemoptysis revealed a suspected aneurysm in the consolidated left lingular lobe; however, this could not be localized via catheter angiography during the pulmonary and bronchial arterial phases. Two weeks later, a massive hemoptysis episode led to haemodynamic instability and serious consequences. Follow‐up CTA confirmed the previously detected aneurysm, and glue embolization was performed successfully. This case report highlights a rare but catastrophic MAC‐associated pseudoaneurysm and relevant treatment options.
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spelling pubmed-53222662017-03-01 Ambiguous presentation of Mycobacterium avium complex‐associated Rasmussen aneurysm Chiu, Hsin‐Wei Kuo, Shu‐Hung Lai, Ruay‐Sheng Wu, Ming‐Ting Wu, Hsiu‐Fu Respirol Case Rep Case Reports A 77‐year‐old man with a progressively dry cough (two months duration) was admitted with hemoptysis. Chest computed tomography (CT) revealed left lingular lobe consolidation and one thick‐walled cavity lesion over the left lower lobe, which was accompanied by satellite micro‐nodules in a tree‐in‐bud pattern. CT‐guided biopsy confirmed mycobacterial infection, and subsequent culture yielded Mycobacterium avium complex (MAC). Unremitting hemoptysis was present despite treatment (14 days) with ethambutol, rifampin, clarithromycin, and streptomycin. Initial CT angiography (CTA) to determine the source of the hemoptysis revealed a suspected aneurysm in the consolidated left lingular lobe; however, this could not be localized via catheter angiography during the pulmonary and bronchial arterial phases. Two weeks later, a massive hemoptysis episode led to haemodynamic instability and serious consequences. Follow‐up CTA confirmed the previously detected aneurysm, and glue embolization was performed successfully. This case report highlights a rare but catastrophic MAC‐associated pseudoaneurysm and relevant treatment options. John Wiley & Sons, Ltd 2017-02-23 /pmc/articles/PMC5322266/ /pubmed/28250929 http://dx.doi.org/10.1002/rcr2.219 Text en © 2017 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Chiu, Hsin‐Wei
Kuo, Shu‐Hung
Lai, Ruay‐Sheng
Wu, Ming‐Ting
Wu, Hsiu‐Fu
Ambiguous presentation of Mycobacterium avium complex‐associated Rasmussen aneurysm
title Ambiguous presentation of Mycobacterium avium complex‐associated Rasmussen aneurysm
title_full Ambiguous presentation of Mycobacterium avium complex‐associated Rasmussen aneurysm
title_fullStr Ambiguous presentation of Mycobacterium avium complex‐associated Rasmussen aneurysm
title_full_unstemmed Ambiguous presentation of Mycobacterium avium complex‐associated Rasmussen aneurysm
title_short Ambiguous presentation of Mycobacterium avium complex‐associated Rasmussen aneurysm
title_sort ambiguous presentation of mycobacterium avium complex‐associated rasmussen aneurysm
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322266/
https://www.ncbi.nlm.nih.gov/pubmed/28250929
http://dx.doi.org/10.1002/rcr2.219
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