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System-based proteomic and metabonomic analysis of the Df(16)A(+/−) mouse identifies potential miR-185 targets and molecular pathway alterations
Deletions on chromosome 22q11.2 are a strong genetic risk factor for development of schizophrenia and cognitive dysfunction. We employed shotgun liquid chromatography–mass spectrometry (LC-MS) proteomic and metabonomic profiling approaches on prefrontal cortex (PFC) and hippocampal (HPC) tissue from...
Autores principales: | Wesseling, H, Xu, B, Want, E J, Holmes, E, Guest, P C, Karayiorgou, M, Gogos, J A, Bahn, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322275/ https://www.ncbi.nlm.nih.gov/pubmed/27001617 http://dx.doi.org/10.1038/mp.2016.27 |
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