Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging

We report development of the first genetically encoded bioluminescent indicator for membrane voltage called LOTUS-V. Since it is bioluminescent, imaging LOTUS-V does not require external light illumination. This allows bidirectional optogenetic control of cellular activity triggered by Channelrhodop...

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Detalles Bibliográficos
Autores principales: Inagaki, Shigenori, Tsutsui, Hidekazu, Suzuki, Kazushi, Agetsuma, Masakazu, Arai, Yoshiyuki, Jinno, Yuka, Bai, Guirong, Daniels, Matthew J., Okamura, Yasushi, Matsuda, Tomoki, Nagai, Takeharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322354/
https://www.ncbi.nlm.nih.gov/pubmed/28205521
http://dx.doi.org/10.1038/srep42398

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