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Existence of HbF Enhancer Haplotypes at HBS1L-MYB Intergenic Region in Transfusion-Dependent Saudi β-Thalassemia Patients

Background and Objectives. β-Thalassemia and sickle cell disease are genetic disorders characterized by reduced and abnormal β-globin chain production, respectively. The elevation of fetal hemoglobin (HbF) can ameliorate the severity of these disorders. In sickle cell disease patients, the HbF level...

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Detalles Bibliográficos
Autores principales:	Cyrus, Cyril, Vatte, Chittibabu, Borgio, J. Francis, Al-Rubaish, Abdullah, Chathoth, Shahanas, Nasserullah, Zaki A., Jarrash, Sana Al, Sulaiman, Ahmed, Qutub, Hatem, Alsaleem, Hassan, Alzahrani, Alhusain J., Steinberg, Martin H., Ali, Amein K. Al
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322420/ https://www.ncbi.nlm.nih.gov/pubmed/28280727 http://dx.doi.org/10.1155/2017/1972429

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