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Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature

We report a case of a 1-month-old infant with spontaneous thymic hemorrhage secondary to severe vitamin K deficiency. He was brought to medical attention due to scrotal bruising and during evaluation was noted to be tachypneic and hypoxemic. Chest X-ray revealed an enlarged cardiothymic silhouette,...

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Autores principales: Palau, Mauricio A., Winters, Amanda, Liang, Xiayuan, Nuss, Rachelle, Niermeyer, Susan, Gossling, Megan, Wright, Clyde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322422/
https://www.ncbi.nlm.nih.gov/pubmed/28280644
http://dx.doi.org/10.1155/2017/7628946
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author Palau, Mauricio A.
Winters, Amanda
Liang, Xiayuan
Nuss, Rachelle
Niermeyer, Susan
Gossling, Megan
Wright, Clyde
author_facet Palau, Mauricio A.
Winters, Amanda
Liang, Xiayuan
Nuss, Rachelle
Niermeyer, Susan
Gossling, Megan
Wright, Clyde
author_sort Palau, Mauricio A.
collection PubMed
description We report a case of a 1-month-old infant with spontaneous thymic hemorrhage secondary to severe vitamin K deficiency. He was brought to medical attention due to scrotal bruising and during evaluation was noted to be tachypneic and hypoxemic. Chest X-ray revealed an enlarged cardiothymic silhouette, and a follow-up echocardiogram revealed a mass in the anterior mediastinum. Routine laboratory work-up revealed severe coagulopathy. Further questioning revealed the patient had not received prophylactic vitamin K at birth. The coagulopathy resolved with administration of vitamin K, and a biopsy confirmed the anterior mediastinal mass was due to spontaneous thymic hemorrhage.
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spelling pubmed-53224222017-03-09 Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature Palau, Mauricio A. Winters, Amanda Liang, Xiayuan Nuss, Rachelle Niermeyer, Susan Gossling, Megan Wright, Clyde Case Rep Pediatr Case Report We report a case of a 1-month-old infant with spontaneous thymic hemorrhage secondary to severe vitamin K deficiency. He was brought to medical attention due to scrotal bruising and during evaluation was noted to be tachypneic and hypoxemic. Chest X-ray revealed an enlarged cardiothymic silhouette, and a follow-up echocardiogram revealed a mass in the anterior mediastinum. Routine laboratory work-up revealed severe coagulopathy. Further questioning revealed the patient had not received prophylactic vitamin K at birth. The coagulopathy resolved with administration of vitamin K, and a biopsy confirmed the anterior mediastinal mass was due to spontaneous thymic hemorrhage. Hindawi Publishing Corporation 2017 2017-02-09 /pmc/articles/PMC5322422/ /pubmed/28280644 http://dx.doi.org/10.1155/2017/7628946 Text en Copyright © 2017 Mauricio A. Palau et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Palau, Mauricio A.
Winters, Amanda
Liang, Xiayuan
Nuss, Rachelle
Niermeyer, Susan
Gossling, Megan
Wright, Clyde
Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature
title Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature
title_full Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature
title_fullStr Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature
title_full_unstemmed Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature
title_short Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature
title_sort vitamin k deficiency presenting in an infant with an anterior mediastinal mass: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322422/
https://www.ncbi.nlm.nih.gov/pubmed/28280644
http://dx.doi.org/10.1155/2017/7628946
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