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The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss

In a previous study, we found that the short isoform of DNAJB6 (DNAJB6(S)) had been decreased in the striatum of a mouse model of Parkinson's disease (PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). DNAJB6, one of the heat shock proteins, has been implicated in the pathogene...

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Detalles Bibliográficos
Autores principales: Hong, Yeon-Mi, Hong, Yohan, Choi, Yeong-Gon, Yeo, Sujung, Jin, Soo Hee, Lee, Sae-Won, Sung, Backil, Lee, Sook-Hyun, Jung, Hyejin, Lim, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322441/
https://www.ncbi.nlm.nih.gov/pubmed/28280525
http://dx.doi.org/10.1155/2017/7982389

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