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Endothelin receptor-specific control of endoplasmic reticulum stress and apoptosis in the kidney

Endothelin-1 (ET-1) promotes renal damage during cardiovascular disease; yet, the molecular mechanisms involved remain unknown. Endoplasmic reticulum (ER) stress, triggered by unfolded protein accumulation in the ER, contributes to apoptosis and organ injury. These studies aimed to determine whether...

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Detalles Bibliográficos
Autores principales:	De Miguel, Carmen, Hamrick, William C., Hobbs, Janet L., Pollock, David M., Carmines, Pamela K., Pollock, Jennifer S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322462/ https://www.ncbi.nlm.nih.gov/pubmed/28230089 http://dx.doi.org/10.1038/srep43152

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