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The Relations Between HSG Proven Tubal Occlusion, Stimulated Intrauterine Insemination and Pregnancy Rate

BACKGROUND: Tubal factor infertility is one of the main causes of female infertility. Although its sensitivity is low, hysterosalpingography (HSG) is remains the first-line method for evaluating tubal patency. AIMS: To compare pregnancy rates in patients with HSG proven proximal or distal unilateral...

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Autores principales: Yetkin Yıldırım, Gonca, Orta Korkut, Ahu, Köroğlu, Nadiye, Susan Türkgeldi, Lale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322513/
https://www.ncbi.nlm.nih.gov/pubmed/28251025
http://dx.doi.org/10.4274/balkanmedj.2016.0289
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author Yetkin Yıldırım, Gonca
Orta Korkut, Ahu
Köroğlu, Nadiye
Susan Türkgeldi, Lale
author_facet Yetkin Yıldırım, Gonca
Orta Korkut, Ahu
Köroğlu, Nadiye
Susan Türkgeldi, Lale
author_sort Yetkin Yıldırım, Gonca
collection PubMed
description BACKGROUND: Tubal factor infertility is one of the main causes of female infertility. Although its sensitivity is low, hysterosalpingography (HSG) is remains the first-line method for evaluating tubal patency. AIMS: To compare pregnancy rates in patients with HSG proven proximal or distal unilateral tubal occlusion, and unexplained infertility undergoing both controlled ovarian stimulation (COS) and intrauterine insemination (IUI). STUDY DESIGN: Case control study. METHODS: In total, 237 patients undergoing ovulation induction (OI) with gonadotropins and IUI were divided into two groups and evaluated. Study group consisted 59 patients with HSG proven unilateral tubal pathology, and 178 patients with unexplained infertility taken as control subjects. Cumulative pregnancy rate was the primary endpoint. RESULTS: Cumulative pregnancy rates after three cycles of OI and IUI were 15.25% in study group and 20.79% in control group. Pregnancy rates between two groups were not statistically significant. Although, pregnancy rates in patients with proximal tubal occlusion (21.8%) were higher than in those with distal tubal occlusion (7.4%), the difference was not statistically significant. CONCLUSION: Our study data shows that, regardless of the HCG proven occlusion area, COS and IUI might be a preferred treatment modality in patient with unilateral tubal occlusion.
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spelling pubmed-53225132017-03-01 The Relations Between HSG Proven Tubal Occlusion, Stimulated Intrauterine Insemination and Pregnancy Rate Yetkin Yıldırım, Gonca Orta Korkut, Ahu Köroğlu, Nadiye Susan Türkgeldi, Lale Balkan Med J Original Article BACKGROUND: Tubal factor infertility is one of the main causes of female infertility. Although its sensitivity is low, hysterosalpingography (HSG) is remains the first-line method for evaluating tubal patency. AIMS: To compare pregnancy rates in patients with HSG proven proximal or distal unilateral tubal occlusion, and unexplained infertility undergoing both controlled ovarian stimulation (COS) and intrauterine insemination (IUI). STUDY DESIGN: Case control study. METHODS: In total, 237 patients undergoing ovulation induction (OI) with gonadotropins and IUI were divided into two groups and evaluated. Study group consisted 59 patients with HSG proven unilateral tubal pathology, and 178 patients with unexplained infertility taken as control subjects. Cumulative pregnancy rate was the primary endpoint. RESULTS: Cumulative pregnancy rates after three cycles of OI and IUI were 15.25% in study group and 20.79% in control group. Pregnancy rates between two groups were not statistically significant. Although, pregnancy rates in patients with proximal tubal occlusion (21.8%) were higher than in those with distal tubal occlusion (7.4%), the difference was not statistically significant. CONCLUSION: Our study data shows that, regardless of the HCG proven occlusion area, COS and IUI might be a preferred treatment modality in patient with unilateral tubal occlusion. Galenos Publishing 2017-01 2017-01-05 /pmc/articles/PMC5322513/ /pubmed/28251025 http://dx.doi.org/10.4274/balkanmedj.2016.0289 Text en © Copyright 2017, Trakya University Faculty of Medicine http://creativecommons.org/licenses/by/2.5/ Balkan Medical Journal
spellingShingle Original Article
Yetkin Yıldırım, Gonca
Orta Korkut, Ahu
Köroğlu, Nadiye
Susan Türkgeldi, Lale
The Relations Between HSG Proven Tubal Occlusion, Stimulated Intrauterine Insemination and Pregnancy Rate
title The Relations Between HSG Proven Tubal Occlusion, Stimulated Intrauterine Insemination and Pregnancy Rate
title_full The Relations Between HSG Proven Tubal Occlusion, Stimulated Intrauterine Insemination and Pregnancy Rate
title_fullStr The Relations Between HSG Proven Tubal Occlusion, Stimulated Intrauterine Insemination and Pregnancy Rate
title_full_unstemmed The Relations Between HSG Proven Tubal Occlusion, Stimulated Intrauterine Insemination and Pregnancy Rate
title_short The Relations Between HSG Proven Tubal Occlusion, Stimulated Intrauterine Insemination and Pregnancy Rate
title_sort relations between hsg proven tubal occlusion, stimulated intrauterine insemination and pregnancy rate
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322513/
https://www.ncbi.nlm.nih.gov/pubmed/28251025
http://dx.doi.org/10.4274/balkanmedj.2016.0289
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