Induced Disruption of the Iron-Regulatory Hormone Hepcidin Inhibits Acute Inflammatory Hypoferraemia

Withdrawal of iron from serum (hypoferraemia) is a conserved innate immune antimicrobial strategy that can withhold this critical nutrient from invading pathogens, impairing their growth. Hepcidin (Hamp1) is the master regulator of iron and its expression is induced by inflammation. Mice lacking Ham...

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Detalles Bibliográficos
Autores principales: Armitage, Andrew E., Lim, Pei Jin, Frost, Joe N., Pasricha, Sant-Rayn, Soilleux, Elizabeth J., Evans, Emma, Morovat, Alireza, Santos, Ana, Diaz, Rebeca, Biggs, Daniel, Davies, Benjamin, Gileadi, Uzi, Robbins, Peter A., Lakhal-Littleton, Samira, Drakesmith, Hal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322583/
https://www.ncbi.nlm.nih.gov/pubmed/27423740
http://dx.doi.org/10.1159/000447713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322583/
https://www.ncbi.nlm.nih.gov/pubmed/27423740
http://dx.doi.org/10.1159/000447713

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