Cargando…

PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes

The discovery of poly(ADP-ribose) >50 years ago opened a new field, leading the way for the discovery of the poly(ADP-ribose) polymerase (PARP) family of enzymes and the ADP-ribosylation reactions that they catalyze. Although the field was initially focused primarily on the biochemistry and molec...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupte, Rebecca, Liu, Ziying, Kraus, W. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322727/
https://www.ncbi.nlm.nih.gov/pubmed/28202539
http://dx.doi.org/10.1101/gad.291518.116