Bax-inhibitor-1 knockdown phenotypes are suppressed by Buffy and exacerbate degeneration in a Drosophila model of Parkinson disease

BACKGROUND: Bax inhibitor-1 (BI-1) is an evolutionarily conserved cytoprotective transmembrane protein that acts as a suppressor of Bax-induced apoptosis by regulation of endoplasmic reticulum stress-induced cell death. We knocked down BI-1 in the sensitive dopa decarboxylase (Ddc) expressing neuron...

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Detalles Bibliográficos
Autores principales: M’Angale, P. Githure, Staveley, Brian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322759/
https://www.ncbi.nlm.nih.gov/pubmed/28243526
http://dx.doi.org/10.7717/peerj.2974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322759/
https://www.ncbi.nlm.nih.gov/pubmed/28243526
http://dx.doi.org/10.7717/peerj.2974

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