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Bax-inhibitor-1 knockdown phenotypes are suppressed by Buffy and exacerbate degeneration in a Drosophila model of Parkinson disease
BACKGROUND: Bax inhibitor-1 (BI-1) is an evolutionarily conserved cytoprotective transmembrane protein that acts as a suppressor of Bax-induced apoptosis by regulation of endoplasmic reticulum stress-induced cell death. We knocked down BI-1 in the sensitive dopa decarboxylase (Ddc) expressing neuron...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PeerJ Inc.
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322759/ https://www.ncbi.nlm.nih.gov/pubmed/28243526 http://dx.doi.org/10.7717/peerj.2974 |