Galectin-3, histone deacetylases, and Hedgehog signaling: Possible convergent targets in schistosomiasis-induced liver fibrosis

Schistosomiasis affects approximately 240 million people in the world. Schistosoma mansoni eggs in the liver induce periportal fibrosis and hepatic failure driven by monocyte recruitment and macrophage activation, resulting in robust Th2 response. Here, we suggested a possible involvement of Galecti...

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Detalles Bibliográficos
Autores principales: de Oliveira, Felipe Leite, Carneiro, Katia, Brito, José Marques, Cabanel, Mariana, Pereira, Jonathas Xavier, Paiva, Ligia de Almeida, Syn, Wingkin, Henderson, Neil C., El-Cheikh, Marcia Cury
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322873/
https://www.ncbi.nlm.nih.gov/pubmed/28231240
http://dx.doi.org/10.1371/journal.pntd.0005137

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