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Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups

Medulloblastoma comprises four main subgroups (WNT, SHH, Group 3 and Group 4) originally defined by transcriptional profiling. In primary medulloblastoma tissues, these groups are thought to be distinguishable using the immunohistochemical detection of β-catenin, filamin A, GAB1 and YAP1 protein mar...

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Detalles Bibliográficos
Autores principales: Chlapek, Petr, Zitterbart, Karel, Kren, Leos, Filipova, Lenka, Sterba, Jaroslav, Veselska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322931/
https://www.ncbi.nlm.nih.gov/pubmed/28231263
http://dx.doi.org/10.1371/journal.pone.0172552

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