Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis

The human papillomavirus (HPV) oncoproteins E6 and E7 are risk factors that are primarily responsible for the initiation and progression of cervical cancer, and they play a key role in immortalization and transformation by reprogramming differentiating host epithelial cells. It is unclear how cervic...

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Detalles Bibliográficos
Autores principales: Feng, Dingqing, Yan, Keqin, Zhou, Ying, Liang, Haiyan, Liang, Jing, Zhao, Weidong, Dong, Zhongjun, Ling, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323100/
https://www.ncbi.nlm.nih.gov/pubmed/27602489
http://dx.doi.org/10.18632/oncotarget.11810

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