Cargando…

Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder characterized by extracellular plaques containing abnormal Amyloid Beta (Aβ) aggregates, intracellular neurofibrillary tangles containing hyperphosphorylated tau protein, microglia-dominated neuroinflammation, and impairments...

Descripción completa

Detalles Bibliográficos
Autores principales:	Braidy, Nady, Essa, Musthafa Mohamed, Poljak, Anne, Selvaraju, Subash, Al-Adawi, Samir, Manivasagm, Thamilarasan, Thenmozhi, Arokiasamy Justin, Ooi, Lezanne, Sachdev, Perminder, Guillemin, Gilles J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323101/ https://www.ncbi.nlm.nih.gov/pubmed/27486879 http://dx.doi.org/10.18632/oncotarget.10905

Ejemplares similares

Pomegranate from Oman Alleviates the Brain Oxidative Damage in Transgenic Mouse Model of Alzheimer's disease
por: Subash, Selvaraju, et al.
Publicado: (2014)

Neuroprotective Effects of Hesperidin, a Plant Flavanone, on Rotenone-Induced Oxidative Stress and Apoptosis in a Cellular Model for Parkinson's Disease
por: Tamilselvam, Kuppusamy, et al.
Publicado: (2013)

Long-Term Dietary Supplementation of Pomegranates, Figs and Dates Alleviate Neuroinflammation in a Transgenic Mouse Model of Alzheimer’s Disease
por: Essa, Musthafa Mohamed, et al.
Publicado: (2015)

Neuroprotective Effects of a Variety of Pomegranate Juice Extracts against MPTP-Induced Cytotoxicity and Oxidative Stress in Human Primary Neurons
por: Braidy, Nady, et al.
Publicado: (2013)

Role of NAD(+), Oxidative Stress, and Tryptophan Metabolism in Autism Spectrum Disorders
por: Essa, Musthafa Mohamed, et al.
Publicado: (2013)

Diet rich in date palm fruits improves memory, learning and reduces beta amyloid in transgenic mouse model of Alzheimer's disease
por: Subash, Selvaraju, et al.
Publicado: (2015)

Neurosupportive Role of Vanillin, a Natural Phenolic Compound, on Rotenone Induced Neurotoxicity in SH-SY5Y Neuroblastoma Cells
por: Dhanalakshmi, Chinnasamy, et al.
Publicado: (2015)

Neuroprotective effects of berry fruits on neurodegenerative diseases
por: Subash, Selvaraju, et al.
Publicado: (2014)

Modulation of GDF11 expression and synaptic plasticity by age and training
por: De Domenico, Emanuela, et al.
Publicado: (2017)

Fenugreek Seed Powder Nullified Aluminium Chloride Induced Memory Loss, Biochemical Changes, Aβ Burden and Apoptosis via Regulating Akt/GSK3β Signaling Pathway
por: Prema, Asokan, et al.
Publicado: (2016)

Catalpol protects synaptic proteins from beta-amyloid induced neuron injury and improves cognitive functions in aged rats
por: Xia, Zhiming, et al.
Publicado: (2017)

Influences of Chronic Mild Stress Exposure on Motor, Non-Motor Impairments and Neurochemical Variables in Specific Brain Areas of MPTP/Probenecid Induced Neurotoxicity in Mice
por: Janakiraman, Udaiyappan, et al.
Publicado: (2016)

The Plasma NAD(+) Metabolome Is Dysregulated in “Normal” Aging
por: Clement, James, et al.
Publicado: (2019)

DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Rapid and simple detection of gero-suppressive agents
por: Darzynkiewicz, Zbigniew
Publicado: (2015)

WW domain-containing oxidoreductase in neuronal injury and neurological diseases
por: Chang, Hsin-Tzu, et al.
Publicado: (2014)

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition
por: Rémond, Didier, et al.
Publicado: (2015)

Measuring refractive index distribution in the human eye lens
por: Pope, James M., et al.
Publicado: (2015)

Characterization and redox mechanism of asthma in the elderly
por: Zuo, Li, et al.
Publicado: (2016)

REM sleep behaviour disorder (RBD): risk for Parkinsonism and executive dysfunction in elderly
por: Lerche, Stefanie, et al.
Publicado: (2018)

TGF-β1-Smad signaling pathways are not required for epidermal LC homeostasis
por: Li, Guihua, et al.
Publicado: (2016)

Reprogramming of energy metabolism as a driver of aging
por: Feng, Zhaoyang, et al.
Publicado: (2016)

Chronic Dietary Supplementation of 4% Figs on the Modification of Oxidative Stress in Alzheimer's Disease Transgenic Mouse Model
por: Subash, Selvaraju, et al.
Publicado: (2014)

Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes
por: Castellano-González, Gloria, et al.
Publicado: (2016)

MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian
por: Mo, Mingshu, et al.
Publicado: (2016)

Transient enhancement of proliferation of neural progenitors and impairment of their long-term survival in p25 transgenic mice
por: Zou, Donghua, et al.
Publicado: (2016)

Loss of myocardial protection against myocardial infarction in middle-aged transgenic mice overexpressing cardiac thioredoxin-1
por: D´Annunzio, Verónica, et al.
Publicado: (2016)

Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice
por: Wang, Fei, et al.
Publicado: (2015)

Demethoxycurcumin, a Natural Derivative of Curcumin Abrogates Rotenone-induced Dopamine Depletion and Motor Deficits by Its Antioxidative and Anti-inflammatory Properties in Parkinsonian Rats
por: Ramkumar, Muthu, et al.
Publicado: (2018)

Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma
por: Wong, Matthew Wai Kin, et al.
Publicado: (2019)

Fluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's disease mice
por: Ma, Jing, et al.
Publicado: (2017)

Recent Neurotherapeutic Strategies to Promote Healthy Brain Aging: Are we there yet?
por: Kim, Chul-Kyu, et al.
Publicado: (2022)

Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cells
por: Ramkumar, Muthu, et al.
Publicado: (2017)

Differential expression of sirtuins in the aging rat brain
por: Braidy, Nady, et al.
Publicado: (2015)

Age and metabolic risk factors associated with oxidatively damaged DNA in human peripheral blood mononuclear cells
por: Løhr, Mille, et al.
Publicado: (2014)

Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain
por: Chang, Jean-Yun, et al.
Publicado: (2015)

Plasmid DNA-coding p62 as a bone effective anti-inflammatory/anabolic agent
por: Sabbieti, Maria Giovanna, et al.
Publicado: (2015)

Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival
por: Kim, Sangkyu, et al.
Publicado: (2015)

The function of cux1 in oxidative dna damage repair is needed to prevent premature senescence of mouse embryo fibroblasts
por: Ramdzan, Zubaidah M., et al.
Publicado: (2015)

DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3ʹ-end GC density
por: Yu, Bo, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_n27rsrtpj330b12ib0q12ki50a