Interferon-gamma deficiency protects against aging-related goblet cell loss

Aging is a well-recognized risk factor for dry eye. Interferon-gamma (IFN-γ) has been implicated in conjunctival keratinization and goblet cell loss in dry eye. We investigated the role of IFN-γ in age-related dry eye by evaluating young (8 weeks) and aged (15 months; 15M) C57BL/6 (B6) and IFN-γKO m...

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Detalles Bibliográficos
Autores principales: Volpe, Eugene A., Henriksson, Johanna Tukler, Wang, Changjun, Barbosa, Flavia L., Zaheer, Mahira, Zhang, Xiaobo, Pflugfelder, Stephen C., de Paiva, Cintia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323102/
https://www.ncbi.nlm.nih.gov/pubmed/27623073
http://dx.doi.org/10.18632/oncotarget.11872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323102/
https://www.ncbi.nlm.nih.gov/pubmed/27623073
http://dx.doi.org/10.18632/oncotarget.11872

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