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Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice

Previous studies based on cell culture and xenograft animal models suggest that Smad3 has tumor suppressor function for breast cancer during early stages of tumorigenesis. In this report, we show that DMBA (7,12-dimethylbenz[a]anthracene), a chemical carcinogen, induces mammary tumor formation at a...

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Detalles Bibliográficos
Autores principales:	Liu, Zhengxue, Kundu-Roy, Tanima, Matsuura, Isao, Wang, Guannan, Lin, Yong, Lou, You-Rong, Barnard, Nicola J., Wang, Xiao-Fan, Huang, Mou-Tuan, Suh, Nanjoo, Liu, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323122/ https://www.ncbi.nlm.nih.gov/pubmed/27588495 http://dx.doi.org/10.18632/oncotarget.11713

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