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An oncogenic role for sphingosine kinase 2

While both human sphingosine kinases (SK1 and SK2) catalyze the generation of the pleiotropic signaling lipid sphingosine 1-phosphate, these enzymes appear to be functionally distinct. SK1 has well described roles in promoting cell survival, proliferation and neoplastic transformation. The roles of...

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Detalles Bibliográficos
Autores principales:	Neubauer, Heidi A., Pham, Duyen H., Zebol, Julia R., Moretti, Paul A.B., Peterson, Amanda L., Leclercq, Tamara M., Chan, Huasheng, Powell, Jason A., Pitman, Melissa R., Samuel, Michael S., Bonder, Claudine S., Creek, Darren J., Gliddon, Briony L., Pitson, Stuart M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323123/ https://www.ncbi.nlm.nih.gov/pubmed/27588496 http://dx.doi.org/10.18632/oncotarget.11714

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