The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer

Ets related gene (ERG) is a transcription factor that is overexpressed in 40% of prostate tumors due to a gene fusion between ERG and TMPRSS2. Because ERG functions as a driver of prostate carcinogenesis, understanding the mechanisms that influence its turnover may provide new molecular handles to t...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Kollipara, Rahul K., Humphries, Caroline G., Ma, Shi-Hong, Hutchinson, Ryan, Li, Rui, Siddiqui, Javed, Tomlins, Scott A., Raj, Ganesh V., Kittler, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323126/
https://www.ncbi.nlm.nih.gov/pubmed/27626314
http://dx.doi.org/10.18632/oncotarget.11915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323126/
https://www.ncbi.nlm.nih.gov/pubmed/27626314
http://dx.doi.org/10.18632/oncotarget.11915

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