Cargando…

Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis

Dysregulation of long non-codng RNA (lncRNA) expression has been found to contribute to tumorigenesis. However, the roles of lncRNAs in BRCA1-related breast cancer remain largely unknown. In this study, we delineate the role of the novel BRCA1/lncRNA NEAT1 signaling axis in breast tumorigenesis. BRC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lo, Pang-Kuo, Zhang, Yongshu, Wolfson, Benjamin, Gernapudi, Ramkishore, Yao, Yuan, Duru, Nadire, Zhou, Qun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323139/ https://www.ncbi.nlm.nih.gov/pubmed/27556296 http://dx.doi.org/10.18632/oncotarget.11364

Ejemplares similares

Characterization of the CD49f(+)/CD44(+)/CD24(−) single-cell derived stem cell population in basal-like DCIS cells
por: Duru, Nadire, et al.
Publicado: (2016)

Loss of miR-140 is a key risk factor for radiation-induced lung fibrosis through reprogramming fibroblasts and macrophages
por: Duru, Nadire, et al.
Publicado: (2016)

Mechanisms of the alternative activation of macrophages and non-coding RNAs in the development of radiation-induced lung fibrosis
por: Duru, Nadire, et al.
Publicado: (2016)

Single-Cell RNA-seq Reveals Obesity-Induced Alterations in the Brca1-Mutated Mammary Gland Microenvironment
por: Lo, Pang-Kuo, et al.
Publicado: (2020)

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity
por: Kim, Myoung Sook, et al.
Publicado: (2017)

HuR‐regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer
por: Chai, Yiqing, et al.
Publicado: (2016)

NEAT1 siRNA Packed with Chitosan Nanoparticles Regulates the Development of Colon Cancer Cells via lncRNA NEAT1/miR-377-3p Axis
por: Li, Tianyu, et al.
Publicado: (2021)

BAP1 dependent expression of long non-coding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinoma
por: Parasramka, Mansi, et al.
Publicado: (2017)

PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma
por: Yi, Kaikai, et al.
Publicado: (2022)

Dysregulation of the centrosome induced by BRCA1 deficiency contributes to tissue‐specific carcinogenesis
por: Yoshino, Yuki, et al.
Publicado: (2021)

NEAT1 as a competing endogenous RNA in tumorigenesis of various cancers: Role, mechanism and therapeutic potential
por: Li, Kun, et al.
Publicado: (2021)

The Implications of the Long Non-Coding RNA NEAT1 in Non-Cancerous Diseases
por: Prinz, Felix, et al.
Publicado: (2019)

Emerging roles of the long non-coding RNA NEAT1 in gynecologic cancers
por: Farzaneh, Maryam, et al.
Publicado: (2023)

Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland
por: Kim, Sun Eui, et al.
Publicado: (2018)

Long non-coding RNA NEAT1 increases the aggressiveness of gastric cancer by regulating the microRNA-142-5p/JAG1 axis
por: Zhang, Yanming, et al.
Publicado: (2021)

Forced isoform switching of Neat1_1 to Neat1_2 leads to the loss of Neat1_1 and the hyperformation of paraspeckles but does not affect the development and growth of mice
por: Isobe, Momo, et al.
Publicado: (2020)

The interplay between ATF2 and NEAT1 contributes to lung adenocarcinoma progression
por: Liu, Jian, et al.
Publicado: (2020)

Long non-coding RNA NEAT1 promotes pulmonary fibrosis by regulating the microRNA-455-3p/SMAD3 axis
por: Liu, Yuan, et al.
Publicado: (2021)

The Long Non-Coding RNA NEAT1 Promotes Gastric Cancer Cell Proliferation and Invasion by Regulating miR-103a/ STAMBPL1 Axis
por: Yu, Da-Jun, et al.
Publicado: (2020)

Pan-cancer analysis of long non-coding RNA NEAT1 in various cancers
por: Li, Shufen, et al.
Publicado: (2017)

Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia
por: Godet, Anne-Claire, et al.
Publicado: (2022)

Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity
por: Wang, Jufang, et al.
Publicado: (2011)

G-Quadruplex Matters in Tissue-Specific Tumorigenesis by BRCA1 Deficiency
por: Kim, Sanghyun, et al.
Publicado: (2022)

KLF5-Modulated lncRNA NEAT1 Contributes to Tumorigenesis by Acting as a Scaffold for BRG1 to Silence GADD45A in Gastric Cancer
por: Ma, Pei, et al.
Publicado: (2020)

LncRNA NEAT1 promotes the tumorigenesis of colorectal cancer by sponging miR‐193a‐3p
por: Yu, Hong‐Mei, et al.
Publicado: (2018)

NEAT1_2–SFPQ axis mediates cisplatin resistance in liver cancer cells in vitro
por: Ru, Yi, et al.
Publicado: (2018)

Recent advances of NEAT1-miRNA interactions in cancer: The interactions of NEAT1 with miRNAs
por: Zhou, Hui, et al.
Publicado: (2022)

Enhanced expression of long non-coding RNA NEAT1 is associated with the progression of gastric adenocarcinomas
por: Ma, Yanling, et al.
Publicado: (2016)

The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states
por: Barry, Guy, et al.
Publicado: (2017)

Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice
por: Kukharsky, Michail S., et al.
Publicado: (2020)

Potential role of long non‐coding RNA H19 and Neat1 in haemophilic arthropathy
por: Sarangi, Pratiksha, et al.
Publicado: (2023)

Cancer stem cells and early stage basal-like breast cancer
por: Lo, Pang-Kuo, et al.
Publicado: (2016)

Neat1 in hematopoietic stem cells
por: Fallik, Noam, et al.
Publicado: (2017)

Proteomics Analysis to Assess the Role of Mitochondria in BRCA1-Mediated Breast Tumorigenesis
por: Concolino, Antonio, et al.
Publicado: (2018)

Long Non-Coding RNA NEAT1 Promoted Hepatocellular Carcinoma Cell Proliferation and Reduced Apoptosis Through the Regulation of Let-7b-IGF-1R Axis
por: Liu, Qin, et al.
Publicado: (2019)

Long non-coding RNA NEAT1/miR-338-3p axis impedes the progression of acute myeloid leukemia via regulating CREBRF
por: Feng, Song, et al.
Publicado: (2020)

Clinical significance of the long non-coding RNA NEAT1/miR-129-5p axis in the diagnosis and prognosis for patients with chronic heart failure
por: Zhang, Haohua, et al.
Publicado: (2021)

Long non-coding RNA NEAT1 facilitates the growth, migration, and invasion of ovarian cancer cells via the let-7 g/MEST/ATGL axis
por: Yin, Lili, et al.
Publicado: (2021)

Neatness
Publicado: (1872)

Dysregulation of SPRR3/miR-876-3p Axis Contributes to Tumorigenesis in Non-Small-Cell Lung Cancer
por: Li, Qin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6m3e58u91bdl1ao7n9o18samd5