The ELK3-GATA3 axis orchestrates invasion and metastasis of breast cancer cells in vitro and in vivo

Triple-negative breast cancer is a highly aggressive tumor subtype that lacks effective therapeutic targets. Here, we show that ELK3 is overexpressed in a subset of breast cancers, in particular basal-like and normal-like/claudin-low cell lines. Suppression of ELK3 in MDA-MB-231 cells led to transdi...

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Detalles Bibliográficos
Autores principales: Kong, Sun-Young, Kim, Kwang-Soo, Kim, Jiewan, Kim, Min Kyeong, Lee, Ki Hong, Lee, Je-Yong, Oh, Nuri, Park, Ji-In, Park, Ji-Hoon, Heo, Sun-Hee, Shim, Sung Han, Lee, Dong Ryul, Kim, Keun Pil, Park, Kyung-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323143/
https://www.ncbi.nlm.nih.gov/pubmed/27556500
http://dx.doi.org/10.18632/oncotarget.11427

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