A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia

Natural killer (NK) cell neoplasms are characterized by clonal proliferation of cytotoxic NK cells. Since there is no standard treatment to date, new therapeutic options are needed, especially for NK aggressive tumors. Fyn tyrosine kinase has a key role in different biological processes, such as cel...

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Detalles Bibliográficos
Autores principales: Laurenzana, Ilaria, Caivano, Antonella, Trino, Stefania, De Luca, Luciana, Rocca, Francesco La, Simeon, Vittorio, Tintori, Cristina, D'Alessio, Francesca, Teramo, Antonella, Zambello, Renato, Traficante, Antonio, Maietti, Maddalena, Semenzato, Gianpietro, Schenone, Silvia, Botta, Maurizio, Musto, Pellegrino, Vecchio, Luigi Del
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323146/
https://www.ncbi.nlm.nih.gov/pubmed/27566560
http://dx.doi.org/10.18632/oncotarget.11496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323146/
https://www.ncbi.nlm.nih.gov/pubmed/27566560
http://dx.doi.org/10.18632/oncotarget.11496

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