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Noninvasive genotyping and monitoring of anaplastic lymphoma kinase (ALK) rearranged non-small cell lung cancer by capture-based next-generation sequencing

Noninvasive genotyping of driver genes and monitoring of tumor dynamics help make better personalized therapeutic decisions. However, neither PCR-based assays nor amplicon-based targeted sequencing can detect fusion genes like anaplastic lymphoma kinase (ALK) rearrangements in blood samples. To inve...

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Detalles Bibliográficos
Autores principales:	Wang, Ye, Tian, Pan-Wen, Wang, Wei-Ya, Wang, Ke, Zhang, Zhou, Chen, Bo-Jiang, He, Yan-Qi, Li, Lei, Liu, Hao, Chuai, Shannon, Li, Wei-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323149/ https://www.ncbi.nlm.nih.gov/pubmed/27564104 http://dx.doi.org/10.18632/oncotarget.11569

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