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O-mannosylation and N-glycosylation: two coordinated mechanisms regulating the tumour suppressor functions of E-cadherin in cancer

Dysregulation of tumor suppressor protein E-cadherin is an early molecular event in cancer. O-mannosylation profile of E-cadherin is a newly-described post-translational modification crucial for its adhesive functions in homeostasis. However, the role of O-mannosyl glycans in E-cadherin-mediated cel...

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Detalles Bibliográficos
Autores principales: Carvalho, Sandra, Oliveira, Tiago, Bartels, Markus F., Miyoshi, Eiji, Pierce, Michael, Taniguchi, Naoyuki, Carneiro, Fátima, Seruca, Raquel, Reis, Celso A., Strahl, Sabine, Pinho, Salomé S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323151/
https://www.ncbi.nlm.nih.gov/pubmed/27533452
http://dx.doi.org/10.18632/oncotarget.11245

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