Leptin promotes migration and invasion of breast cancer cells by stimulating IL-8 production in M2 macrophages

This study aims to investigate the mechanisms underlying leptin-mediated crosstalk between tumor-associated macrophages (M2 macrophages) and breast cancer cells. THP1 human leukemic monocytes were induced to differentiate into M2 macrophages by PMA (100 nM) and IL-4 (20 ng/mL). Quantitative RT-PCR a...

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Detalles Bibliográficos
Autores principales: Cao, Hong, Huang, Yunxiu, Wang, Lin, Wang, Hong, Pang, Xueli, Li, Kuangfa, Dang, Weiqi, Tang, Hao, Wei, Lan, Su, Min, Tang, Cuiping, Chen, Tingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323167/
https://www.ncbi.nlm.nih.gov/pubmed/27588409
http://dx.doi.org/10.18632/oncotarget.11761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323167/
https://www.ncbi.nlm.nih.gov/pubmed/27588409
http://dx.doi.org/10.18632/oncotarget.11761

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