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Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer

HER3/ErbB3 has emerged as a new therapeutic target for cancer. Currently, more than a dozen anti-HER3 antibodies are in clinical trials for treatment of various cancers. However, limited understanding of the complex HER3 signaling in cancer and lack of established biomarkers have made it challenging...

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Detalles Bibliográficos
Autores principales: Zhang, Shu, Mukherjee, Seema, Fan, Xuejun, Salameh, Ahmad, Mujoo, Kalpana, Huang, Zhao, Li, Leike, Salazar, Georgina To'a, Zhang, Ningyan, An, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323190/
https://www.ncbi.nlm.nih.gov/pubmed/27582551
http://dx.doi.org/10.18632/oncotarget.11613

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