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Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia

Ikaros and Foxp1 are transcription factors that play key roles in normal lymphopoiesis and lymphoid malignancies. We describe a novel physical and functional interaction between the proteins, which requires the central zinc finger domain of Ikaros. The Ikaros-Foxp1 interaction is abolished by deleti...

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Detalles Bibliográficos
Autores principales:	Bond, Jonathan, Domaschenz, Renae, Roman-Trufero, Mónica, Sabbattini, Pierangela, Ferreiros-Vidal, Isabel, Gerrard, Gareth, Asnafi, Vahid, Macintyre, Elizabeth, Merkenschlager, Matthias, Dillon, Niall
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323203/ https://www.ncbi.nlm.nih.gov/pubmed/27588474 http://dx.doi.org/10.18632/oncotarget.11688

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