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15-Hydroxyprostaglandin dehydrogenase as a marker in colon carcinogenesis: analysis of the prostaglandin pathway in human colonic tissue

BACKGROUND/AIMS: Cyclooxygenase-2 (COX-2), 15-hydroxyprostaglandin dehydrogenase (15-PGDH), and microsomal prostaglandin E synthase-1 (mPGEs-1) regulate prostaglandin E(2) (PGE(2)) expression and are involved in colon carcinogenesis. We investigated the expression of PGE(2) and its regulating genes...

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Detalles Bibliográficos
Autores principales: Yang, Dong-Hoon, Ryu, Yeon-Mi, Lee, Sun-Mi, Jeong, Jin-Yong, Yoon, Soon Man, Ye, Byong Duk, Byeon, Jeong-Sik, Yang, Suk-Kyun, Myung, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for the Study of Intestinal Diseases 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323311/
https://www.ncbi.nlm.nih.gov/pubmed/28239316
http://dx.doi.org/10.5217/ir.2017.15.1.75