Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases

Yīn-Chén-Hāo decoction (YCHD) is a traditional Chinese medicine formula composed of capillaris (Artemisia capillaris), gardenia (Gardenia jasminoides), and rhubarb (Rheum rhabarbarum) that is used for the treatment of damp-heat jaundice. In modern clinics, YCHD is mostly used for hepatic diseases. T...

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Autores principales: Li, Jian-Yuan, Cao, Hong-Yan, Sun, Lin, Sun, Run-Fei, Wu, Chao, Bian, Yan-Qin, Dong, Shu, Liu, Ping, Sun, Ming-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323438/
https://www.ncbi.nlm.nih.gov/pubmed/28275293
http://dx.doi.org/10.3748/wjg.v23.i7.1125
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author Li, Jian-Yuan
Cao, Hong-Yan
Sun, Lin
Sun, Run-Fei
Wu, Chao
Bian, Yan-Qin
Dong, Shu
Liu, Ping
Sun, Ming-Yu
author_facet Li, Jian-Yuan
Cao, Hong-Yan
Sun, Lin
Sun, Run-Fei
Wu, Chao
Bian, Yan-Qin
Dong, Shu
Liu, Ping
Sun, Ming-Yu
author_sort Li, Jian-Yuan
collection PubMed
description Yīn-Chén-Hāo decoction (YCHD) is a traditional Chinese medicine formula composed of capillaris (Artemisia capillaris), gardenia (Gardenia jasminoides), and rhubarb (Rheum rhabarbarum) that is used for the treatment of damp-heat jaundice. In modern clinics, YCHD is mostly used for hepatic diseases. This review summarizes the biological activities of YCHD and its medical applications. The main active compounds of YCHD are chlorogenic acid, rhein, geniposide, emodin, and scoparone. The pharmacological actions of YCHD include inhibition of hepatic steatosis, apoptosis, necrosis, anti-inflammation, and immune regulation. YCHD could be developed as a new therapeutic strategy for the treatment of hepatic diseases.
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spelling pubmed-53234382017-03-08 Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases Li, Jian-Yuan Cao, Hong-Yan Sun, Lin Sun, Run-Fei Wu, Chao Bian, Yan-Qin Dong, Shu Liu, Ping Sun, Ming-Yu World J Gastroenterol Review Yīn-Chén-Hāo decoction (YCHD) is a traditional Chinese medicine formula composed of capillaris (Artemisia capillaris), gardenia (Gardenia jasminoides), and rhubarb (Rheum rhabarbarum) that is used for the treatment of damp-heat jaundice. In modern clinics, YCHD is mostly used for hepatic diseases. This review summarizes the biological activities of YCHD and its medical applications. The main active compounds of YCHD are chlorogenic acid, rhein, geniposide, emodin, and scoparone. The pharmacological actions of YCHD include inhibition of hepatic steatosis, apoptosis, necrosis, anti-inflammation, and immune regulation. YCHD could be developed as a new therapeutic strategy for the treatment of hepatic diseases. Baishideng Publishing Group Inc 2017-02-21 2017-02-21 /pmc/articles/PMC5323438/ /pubmed/28275293 http://dx.doi.org/10.3748/wjg.v23.i7.1125 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Review
Li, Jian-Yuan
Cao, Hong-Yan
Sun, Lin
Sun, Run-Fei
Wu, Chao
Bian, Yan-Qin
Dong, Shu
Liu, Ping
Sun, Ming-Yu
Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases
title Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases
title_full Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases
title_fullStr Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases
title_full_unstemmed Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases
title_short Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases
title_sort therapeutic mechanism of yīn-chén-hāo decoction in hepatic diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323438/
https://www.ncbi.nlm.nih.gov/pubmed/28275293
http://dx.doi.org/10.3748/wjg.v23.i7.1125
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