Cargando…
Cell Migration: Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation (Adv. Sci. 2/2017)
Mesenchymal stem cells, harvested from the bone marrow, alter their behavior depending on the local curvature of the 3D‐printed surfaces they are seeded upon, as described by Ansgar Petersen and co‐workers in article number 1600347. While concave surfaces promote stem cell migration, convex surfaces...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323641/ http://dx.doi.org/10.1002/advs.201770007 |
_version_ | 1782510064471375872 |
---|---|
author | Werner, Maike Blanquer, Sébastien B. G. Haimi, Suvi P. Korus, Gabriela Dunlop, John W. C. Duda, Georg N. Grijpma, Dirk. W. Petersen, Ansgar |
author_facet | Werner, Maike Blanquer, Sébastien B. G. Haimi, Suvi P. Korus, Gabriela Dunlop, John W. C. Duda, Georg N. Grijpma, Dirk. W. Petersen, Ansgar |
author_sort | Werner, Maike |
collection | PubMed |
description | Mesenchymal stem cells, harvested from the bone marrow, alter their behavior depending on the local curvature of the 3D‐printed surfaces they are seeded upon, as described by Ansgar Petersen and co‐workers in article number 1600347. While concave surfaces promote stem cell migration, convex surfaces enhance cell specification into bone cells, a process driven by curvature‐dependent forces on the cell's nucleus. [Image: see text] |
format | Online Article Text |
id | pubmed-5323641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-53236412017-03-01 Cell Migration: Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation (Adv. Sci. 2/2017) Werner, Maike Blanquer, Sébastien B. G. Haimi, Suvi P. Korus, Gabriela Dunlop, John W. C. Duda, Georg N. Grijpma, Dirk. W. Petersen, Ansgar Adv Sci (Weinh) Inside Front Cover Mesenchymal stem cells, harvested from the bone marrow, alter their behavior depending on the local curvature of the 3D‐printed surfaces they are seeded upon, as described by Ansgar Petersen and co‐workers in article number 1600347. While concave surfaces promote stem cell migration, convex surfaces enhance cell specification into bone cells, a process driven by curvature‐dependent forces on the cell's nucleus. [Image: see text] John Wiley and Sons Inc. 2017-02-24 /pmc/articles/PMC5323641/ http://dx.doi.org/10.1002/advs.201770007 Text en © 2017 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Inside Front Cover Werner, Maike Blanquer, Sébastien B. G. Haimi, Suvi P. Korus, Gabriela Dunlop, John W. C. Duda, Georg N. Grijpma, Dirk. W. Petersen, Ansgar Cell Migration: Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation (Adv. Sci. 2/2017) |
title | Cell Migration: Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation (Adv. Sci. 2/2017) |
title_full | Cell Migration: Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation (Adv. Sci. 2/2017) |
title_fullStr | Cell Migration: Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation (Adv. Sci. 2/2017) |
title_full_unstemmed | Cell Migration: Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation (Adv. Sci. 2/2017) |
title_short | Cell Migration: Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation (Adv. Sci. 2/2017) |
title_sort | cell migration: surface curvature differentially regulates stem cell migration and differentiation via altered attachment morphology and nuclear deformation (adv. sci. 2/2017) |
topic | Inside Front Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323641/ http://dx.doi.org/10.1002/advs.201770007 |
work_keys_str_mv | AT wernermaike cellmigrationsurfacecurvaturedifferentiallyregulatesstemcellmigrationanddifferentiationviaalteredattachmentmorphologyandnucleardeformationadvsci22017 AT blanquersebastienbg cellmigrationsurfacecurvaturedifferentiallyregulatesstemcellmigrationanddifferentiationviaalteredattachmentmorphologyandnucleardeformationadvsci22017 AT haimisuvip cellmigrationsurfacecurvaturedifferentiallyregulatesstemcellmigrationanddifferentiationviaalteredattachmentmorphologyandnucleardeformationadvsci22017 AT korusgabriela cellmigrationsurfacecurvaturedifferentiallyregulatesstemcellmigrationanddifferentiationviaalteredattachmentmorphologyandnucleardeformationadvsci22017 AT dunlopjohnwc cellmigrationsurfacecurvaturedifferentiallyregulatesstemcellmigrationanddifferentiationviaalteredattachmentmorphologyandnucleardeformationadvsci22017 AT dudageorgn cellmigrationsurfacecurvaturedifferentiallyregulatesstemcellmigrationanddifferentiationviaalteredattachmentmorphologyandnucleardeformationadvsci22017 AT grijpmadirkw cellmigrationsurfacecurvaturedifferentiallyregulatesstemcellmigrationanddifferentiationviaalteredattachmentmorphologyandnucleardeformationadvsci22017 AT petersenansgar cellmigrationsurfacecurvaturedifferentiallyregulatesstemcellmigrationanddifferentiationviaalteredattachmentmorphologyandnucleardeformationadvsci22017 |